Compile Data Set for Download or QSAR
maximum 50k data
Found 202 of ic50 data for polymerid = 2444,49000963,49000964
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095207(CHEMBL430154 | [6-(4-Benzhydryl-pyrazol-1-ylmethyl...)
Affinity DataIC50:  8nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  8.40nMAssay Description:Binding affinity to human PGI2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  9nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]iloprost from human recombinant IP receptor expressed in HEK293 cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]iloprost from human recombinant Prostanoid IP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284372(CHEMBL11211 | {5-[2-(N',N'-Diphenyl-hydrazinocarbo...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235375(CHEMBL3975122)
Affinity DataIC50:  12nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50163291(CHEMBL3793903)
Affinity DataIC50:  13nMAssay Description:Agonist activity at human IP receptor in platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1 min follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to PGI2 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235370(CHEMBL3933704)
Affinity DataIC50:  18nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284377(CHEMBL11746 | {5-[2-(4-Benzhydryl-pyrazol-1-yl)-et...)
Affinity DataIC50:  18nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235378(CHEMBL3981509)
Affinity DataIC50:  19nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284370(CHEMBL10836 | [6-(N',N'-Diphenyl-hydrazinocarbonyl...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for prostacyclin (PGI-2) binding by displacement of [3H]-iloprost from human platelets using conventional ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235368(CHEMBL3893346)
Affinity DataIC50:  22nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235373(CHEMBL3928729)
Affinity DataIC50:  23nMAssay Description:Compound was tested for its inhibitory activity against cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235376(CHEMBL3926078)
Affinity DataIC50:  23nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50016954(CHEMBL1628262)
Affinity DataIC50:  25nMAssay Description:Agonist activity at prostanoid IP receptor (unknown origin) by functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235367(CHEMBL3952237)
Affinity DataIC50:  25nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  27nMAssay Description:Prostaglandin I2 receptor binding by displacement of [3H]-iloprost from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235389(CHEMBL3983767)
Affinity DataIC50:  30nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85602((R)-BUTAPROST | Butaprost (Free Acid) | CAS_69648-...)
Affinity DataIC50:  37nMAssay Description:Agonist activity at prostanoid IP receptor (unknown origin) by functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)
Affinity DataIC50:  38nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50191135(CHEMBL215442 | sodium 2-(3-(((1S,2R)-2-(4,5-diphen...)
Affinity DataIC50:  39nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235374(CHEMBL3935924)
Affinity DataIC50:  39nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284378(CHEMBL11765 | [6-(4-Benzhydryl-pyrazol-1-ylmethyl)...)
Affinity DataIC50:  40nMAssay Description:Compound was tested for its binding affinity against Prostaglandin I2 receptor using conventional ligand assay by the displacement of [3H]-iloprost f...More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235379(CHEMBL3932106 | US10668033, Compound 55)
Affinity DataIC50:  43nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50191133(CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...)
Affinity DataIC50:  48nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50191134(CHEMBL379203 | sodium 2-(3-(((1S,2S)-2-(4,5-diphen...)
Affinity DataIC50:  53nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23960(5-(4-phenylbenzyl)oxazole-4-carboxamide, 6g | 5-{[...)
Affinity DataIC50:  53nM EC50:  51nMpH: 7.4 T: 2°CAssay Description:IP receptor binding activity was quantified via a filter binding assay measuring displacement of [3H]-Iloprost binding to human platelet membranes. R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235372(CHEMBL3966307)
Affinity DataIC50:  54nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235384(CHEMBL3900038)
Affinity DataIC50:  54nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50191132(CHEMBL438092 | sodium (S)-2-(3-((2-(4,5-diphenylox...)
Affinity DataIC50:  58nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50136234(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Affinity DataIC50:  60nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235383(ACT-293987 | NS-304 | Selexipag | Uptravi)
Affinity DataIC50:  62nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103396(CHEMBL3398236)
Affinity DataIC50:  62nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103395(CHEMBL3398235)
Affinity DataIC50:  62nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103394(CHEMBL3398229)
Affinity DataIC50:  64nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23953(5-(4-phenylbenzyl)oxazole-4-carboxamide, 6a | 5-{[...)
Affinity DataIC50:  77nMpH: 7.4 T: 2°CAssay Description:IP receptor binding activity was quantified via a filter binding assay measuring displacement of [3H]-Iloprost binding to human platelet membranes. R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095203(CHEMBL94751 | [(S)-6-(3-Benzhydryl-6-oxo-6H-pyrida...)
Affinity DataIC50:  81nMAssay Description:Agonist activity at PGI2 receptor in Homo sapiens (human) platelets assessed as inhibition of ADP-induced aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095203(CHEMBL94751 | [(S)-6-(3-Benzhydryl-6-oxo-6H-pyrida...)
Affinity DataIC50:  81nMAssay Description:Agonist activity at PGI2 in human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103404(CHEMBL3398228)
Affinity DataIC50:  87nMAssay Description:Agonist activity at human IP receptor in human platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235371(CHEMBL3922000)
Affinity DataIC50:  93nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50191137(CHEMBL212943 | sodium 2-(3-(((1S,2R)-2-(4,5-diphen...)
Affinity DataIC50:  114nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50191138(CHEMBL405770 | sodium 2-(3-(((1S,2S)-2-(4,5-diphen...)
Affinity DataIC50:  115nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50163296(CHEMBL3793911)
Affinity DataIC50:  130nMAssay Description:Agonist activity at human IP receptor in platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1 min follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50235377(CHEMBL3890685)
Affinity DataIC50:  142nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095205((6-{2-[(E)-Benzhydryloxyimino]-pentyl}-5,6,7,8-tet...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284366((6-{2-[(E)-Benzhydryloxyimino]-butyl}-5,6,7,8-tetr...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstacyclin receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50002404(9-(3,4,5-Triphenyl-pyrazol-1-yl)-nonanoic acid | C...)
Affinity DataIC50:  160nMAssay Description:IC50 value of the compound was evaluated by measuring the displacement of [3H]-iloprost from Prostaglandin I2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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